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Apr 10, 2023

We’re digging into the MTHFR gene variant and why this matters when you are TTC.

You may have heard about the importance of getting tested for the MTHFR gene variant if you are trying to conceive.

MTHFR variants are associated with difficult conception and early pregnancy loss due to problems with the endometrium and implantation.

IVF studies have shown that women with MTHFR mutations are more likely to experience recurrent implantation failure.

Some men with fertility problems have low MTHFR function in their sperm.

You can’t change your genes, but there is a lot you can do to support your nutrient levels, bypassing the MTHFR enzyme. These include lifestyle changes, dietary habits, and supplementation.

Today I’m excited to welcome Ricardo Miranda. Ricardo is the CEO of He is a clinician and one of the top researchers in the field of MTHFR genetic mutation.


In this episode, you'll learn:

1) Why addressing MTHFR is essential when you are on the fertility journey (i.e. which supplement is essential and what so many people are still getting this wrong)

2) What studies tell us about MTHFR and optimal fertility

3) The link between miscarriage and MTHFR gene variant

4) Why testing blood homocysteine is crucial, and it’s still not a standard of care in conventional medicine

5) Specific diet and lifestyle strategies and exactly which markers to test



Fab Fertile Method


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I'm excited to introduce you to the Inito fertility monitor, an easy, at-home fertility tracker that tells you when you're the most fertile by measuring estrogen and LH and confirms if you’ve actually ovulated by measuring progesterone.

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Join my FREE Facebook group and get my training on HOW to improve pregnancy success with your own eggs.



Ready to get a plan for 2023 to have your baby?

In this personalized consultation, you receive a full review of your fertility history so that we can develop a plan to improve your chances of pregnancy success with your eggs.

Book your call here with your partner:


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Please note when promoting a product, we only select products that either Sarah Clark or her team has tried and believe are beneficial for someone who is TTC. We may receive a small commission.